Nishant

December 30, 2010
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Terrible Month, Good Year

There were days when I spent my entire time coughing, and because of bad cough I couldn’t sleep in the nights either. … There is some control still remaining in the fingers of my left hand thus allowing me to use my computer with the aid of a switch. … There is few more days of work remaining in the completion of my book, hopefully I will be done with it in the first week of January.

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November 30, 2010
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Clinical Results from Phase 1 NP001 Study in the Treatment of ALS

A double-blinded, placebo-controlled, Phase 1, single ascending dose study was performed to assess the safety and tolerability of four single intravenous doses of NP001 in a total 32 individuals with ALS. … Importantly, following a single dose, there was a dose-dependent, statistically significant improvement in blood levels of the biomarker thought to be involved in ALS disease progression; this is a first in ALS. … Miller, M.D., the study’s principal investigator and Medical and Program Director of the Forbes Norris MDA/ALS Research Center, commented, “NP001 appears to have affected the level of a biomarker directly related to ALS pathogenesis in a dose-dependent manner.

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November 22, 2010
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Cough, Cough And More Cough

For the past four days all I have been doing is trying to cough. Problem with cough starts around three in the afternoon and it only gets over around midnight. In past it never lasted for so long and wasn’t this intense either. The good part is that I don’t have fever or any kind [...]

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November 9, 2010
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What My Doctor Says

Yesterday I visited my neurologist after a gap of six months. He did some basic physical examination and told me that I am doing pretty good for my situation. We talked about the pain I am experiencing and he told me that I need something stronger than what I am taking at present. So to [...]

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September 23, 2010
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Four Years And Counting

September marks the four year anniversary of the onset of my disease, and three year anniversary of the diagnosis. Over all these years my disease hasn’t stopped progressing and it is it isn’t showing any signs of slowing down either, but I am one tough cookie as well. I have learnt to live with it [...]

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